A large suspension bridge over a body of water with a cloudy sky in the background.

Find Business Hotels in Mount Pleasant, SC

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Mount Pleasant Business Hotels

Tonight
1 Oct - 2 Oct
Tomorrow
2 Oct - 3 Oct
This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

Our top choices for Mount Pleasant business-friendly hotels

A modern bar area with a wooden ceiling, bar stools, and a counter.
A modern lobby with a curved wooden wall, a central seating area with a blue sofa, and a large framed artwork on the wall.
A gym with treadmills, weight machines, and a mirror.
A modern lounge area with a black sofa, wooden stools, and contemporary chairs.

1. Cambria Hotel Mount Pleasant – Charleston

Cambria Hotel Mount Pleasant – Charleston
Mount Pleasant
United States
Fred V.
AED 457
AED 520 total
includes taxes & fees
4 Oct - 5 Oct
Cambria Hotel Mount Pleasant – Charleston
A modern lobby with seating areas, a reception desk, and decorative lighting.
A multi-story hotel with a modern design, featuring a parking lot and landscaped areas.
A modern hotel with a pool, surrounded by trees and a sunset sky.
A modern lounge area with seating, a counter, and hanging chairs.

2. Tru by Hilton Mt Pleasant Charleston

Tru by Hilton Mt Pleasant Charleston
Mount Pleasant
United States
Mary
AED 403
AED 462 total
includes taxes & fees
18 Oct - 19 Oct
Tru by Hilton Mt Pleasant Charleston
A swimming pool with lounge chairs and umbrellas, surrounded by trees and a building with multiple windows.
A hotel room with a sofa, two beds, a desk, and a window with a view.
A modern hotel room with a flat-screen TV, a wooden dresser, a blue sofa, a desk with a chair, and a painting on the wall.
A modern living room with a sectional sofa, a coffee table, a chair, and a flat-screen TV mounted on the wall.

3. Holiday Inn Express & Suites Mt. Pleasant by IHG

Holiday Inn Express & Suites Mt. Pleasant by IHG
Mount Pleasant
United States
Tami
AED 400
AED 461 total
includes taxes & fees
4 Oct - 5 Oct
Holiday Inn Express & Suites Mt. Pleasant by IHG
A spacious lobby with a high ceiling, a mezzanine level, and multiple seating areas including sofas and chairs.
A two-story building with a covered entrance, palm trees, and a well-maintained lawn.
A clean, well-lit breakfast area with wooden cabinets, a coffee machine, and a microwave.
A pool area with lounge chairs and a brick building in the background.

4. Comfort Inn & Suites Patriots Point

Comfort Inn & Suites Patriots Point
Mount Pleasant
United States
Sandra
AED 364
AED 412 total
includes taxes & fees
4 Oct - 5 Oct
Comfort Inn & Suites Patriots Point
A modern bar area with a long counter, multiple shelves of liquor bottles, a flat-screen TV, and bar stools.
An outdoor patio with brick walls, a fire pit, and outdoor furniture.
A modern living room with a sofa, TV, and a view of greenery outside.
A modern office space with a large desk, multiple chairs, a computer, and a view of the outdoors through large windows.

5. Hyatt House Charleston / Mount Pleasant

Hyatt House Charleston / Mount Pleasant
Mount Pleasant
United States
Samantha
AED 433
AED 498 total
includes taxes & fees
7 Oct - 8 Oct
Hyatt House Charleston / Mount Pleasant
A modern restaurant with brick walls, black furniture, and pendant lighting.
A spacious living area with a blue sofa set, a glass railing, and a modern kitchen in the background.
A multi-story hotel with a modern design, featuring large windows and a flat roof.
A balcony with a black and white patterned sofa, yellow ottomans, and a small table.

6. Hyatt Place Mount Pleasant Towne Centre

Hyatt Place Mount Pleasant Towne Centre
Mount Pleasant
United States
SHARON
AED 427
AED 527 total
includes taxes & fees
11 Oct - 12 Oct
Hyatt Place Mount Pleasant Towne Centre
A spacious dining area with multiple tables and chairs, large windows, and potted plants.
A living room with a sofa, two armchairs, a coffee table, and framed pictures on the wall.
A snack and beverage display area with various snacks and bottled water.
A hotel entrance with a covered walkway, palm trees, and potted plants.

7. Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms

Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms
Mount Pleasant
United States
Daniel
AED 419
AED 481 total
includes taxes & fees
1 Nov - 2 Nov
Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms
A hotel lobby with a bar area, multiple dining tables, and chairs.
A spacious lobby with a high ceiling, a staircase with a wooden handrail, and a seating area with patterned cushions.
A modern kitchen with a central island, bar stools, and a variety of kitchen appliances.
A rooftop patio with outdoor seating, a fire pit, and a view of a multi-story building with balconies.

8. Hilton Garden Inn Charleston / Mt. Pleasant

Hilton Garden Inn Charleston / Mt. Pleasant
Mount Pleasant
United States
Susan
AED 465
AED 526 total
includes taxes & fees
1 Nov - 2 Nov
Hilton Garden Inn Charleston / Mt. Pleasant
A spacious lobby with high ceilings, large windows, and elegant furniture.
An aerial view of a residential area with a swimming pool surrounded by palm trees and a circular patio area.
A spacious living area with a dark wood floor, a central dining table, and a large TV mounted on a dark wood cabinet.
An outdoor patio area with a circular fire pit, lounge chairs, and a brick building with arched windows.

9. Courtyard by Marriott Charleston Mount Pleasant

Courtyard by Marriott Charleston Mount Pleasant
Mount Pleasant
United States
Cynthia
AED 408
AED 461 total
includes taxes & fees
11 Oct - 12 Oct
Courtyard by Marriott Charleston Mount Pleasant
A pool area with lounge chairs and palm trees.
A modern restaurant with a long counter, multiple dining tables, and a seating area with sofas.
A hotel outdoor seating area with wicker chairs, a pool, and palm trees.
A modern kitchen with a central island, built-in shelves, and a variety of kitchen appliances.

10. Hotel Indigo Mount Pleasant by IHG

Hotel Indigo Mount Pleasant by IHG
Mount Pleasant
United States
Linda C
AED 331
AED 447 total
includes taxes & fees
1 Nov - 2 Nov
Hotel Indigo Mount Pleasant by IHG
View all properties

Top Mount Pleasant Hotel Reviews

Harborside at Charleston Harbor Resort and Marina

Harborside at Charleston Harbor Resort and Marina

10/10 Excellent
"Our stay was awesome! Charleston Harbor employees were very helpful! The Downtown free van shuttle service made going downtown so easy. The van drivers were so nice and helpful too! We love staying at Charleston Harbor Resort!"
Sherry 3-night trip
Posted 1 hour ago
Harborside at Charleston Harbor Resort and Marina
Hilton Garden Inn Charleston / Mt. Pleasant

Hilton Garden Inn Charleston / Mt. Pleasant

8/10 Good
"The are fabulous, they were professional and very helpful. The overall cleanliness and attention to details to minor areas like corners, residue from soap or the hair of the previous guest was very evident. It also appear we are paying more for goods and services, but getting less."
Randolph 1-night trip
Posted 5 hours ago
Hilton Garden Inn Charleston / Mt. Pleasant
Sleep Inn Mt. Pleasant - Charleston

Sleep Inn Mt. Pleasant - Charleston

8/10 Good
"Nice basic no frills hotel. The staff was so friendly and accommodating. The room was very clean with tile floors, which I prefer over carpet. Every request was quickly answered. The breakfast buffet was disappointing."
James 2-night trip
Posted 16 hours ago
Sleep Inn Mt. Pleasant - Charleston
Quality Inn Mt. Pleasant - Charleston

Quality Inn Mt. Pleasant - Charleston

8/10 Good
"Beds were comfy...breakfast could use improvement."
Steve 1-night trip
Posted 20 hours ago
Quality Inn Mt. Pleasant - Charleston

Explore a world of travel with Expedia