A large suspension bridge over a body of water with a cloudy sky in the background.

Find Business Hotels in Mount Pleasant, SC

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Mount Pleasant Business Hotels

Our top choices for Mount Pleasant business-friendly hotels

Terrace/patio

Holiday Inn Express & Suites Mt. Pleasant by IHG

Holiday Inn Express & Suites Mt. Pleasant by IHG
3.5 star property
Mount Pleasant
9.2 out of 10, Wonderful, (1,021 reviews)
"Clean hotel, great coffee, and nice people."
United States
Abigail
The price is AED 381
AED 438 total
includes taxes & fees
19 Jul - 20 Jul
Holiday Inn Express & Suites Mt. Pleasant by IHG
Free daily full breakfast

Residence Inn by Marriott Charleston Mount Pleasant

Residence Inn by Marriott Charleston Mount Pleasant
3.0 star property
Mount Pleasant
8.8 out of 10, Excellent, (208 reviews)
"Easy check in, great room, and quiet - everything I needed! "
United States
Tiffany
The price is AED 492
AED 556 total
includes taxes & fees
9 Aug - 10 Aug
Residence Inn by Marriott Charleston Mount Pleasant
2 outdoor pools, free cabanas, pool umbrellas

The Beach Club at Charleston Harbor Resort and Marina

The Beach Club at Charleston Harbor Resort and Marina
4.5 star property
Mount Pleasant
9.2 out of 10, Wonderful, (1,034 reviews)
"The hotel was very nice. Great room and access to both downtown and Sullivan Island."
United States
RYAN
The price is AED 658
AED 918 total
includes taxes & fees
9 Aug - 10 Aug
The Beach Club at Charleston Harbor Resort and Marina
Restaurant

Hilton Garden Inn Charleston / Mt. Pleasant

Hilton Garden Inn Charleston / Mt. Pleasant
3.0 star property
Mount Pleasant
9.0 out of 10, Wonderful, (1,016 reviews)
"Mealtime staff was fabulous"
United States
Gail
The price is AED 443
AED 500 total
includes taxes & fees
2 Aug - 3 Aug
Hilton Garden Inn Charleston / Mt. Pleasant
Exterior

Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG

Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG
2.5 star property
Mount Pleasant
8.8 out of 10, Excellent, (1,000 reviews)
"Room was clean and nice"
United States
Roger
The price is AED 408
AED 461 total
includes taxes & fees
19 Jul - 20 Jul
Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG
Lobby

Comfort Inn & Suites Patriots Point

Comfort Inn & Suites Patriots Point
2.5 star property
Mount Pleasant
8.8 out of 10, Excellent, (1,201 reviews)
"Great place to stay, close to a lot of the sites and easy to get in and out."
United States
BRYAN
The price is AED 465
AED 525 total
includes taxes & fees
19 Jul - 20 Jul
Comfort Inn & Suites Patriots Point
Dinner served

Cambria Hotel Mount Pleasant – Charleston

Cambria Hotel Mount Pleasant – Charleston
3.0 star property
Mount Pleasant
9.4 out of 10, Exceptional, (2,254 reviews)
"Clean rooms, friendly staff, and convenient location."
United States
Randall
The price is AED 521
AED 592 total
includes taxes & fees
12 Aug - 13 Aug
Cambria Hotel Mount Pleasant – Charleston
Restaurant

Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms

Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms
2.5 star property
Mount Pleasant
9.0 out of 10, Wonderful, (1,000 reviews)
"My family and I had a great stay. The room was clean and comfortable, and we appreciated that breakfast was available until 10 a.m. The location was also very convenient, with the beach, stores, and restaurants all close by."
United States
Viviana
The price is AED 479
AED 549 total
includes taxes & fees
11 Aug - 12 Aug
Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms
Outdoor pool, free cabanas, sun loungers

Hotel Indigo Mount Pleasant by IHG

Hotel Indigo Mount Pleasant by IHG
3.5 star property
Mount Pleasant
9.0 out of 10, Wonderful, (1,022 reviews)
"Nice place"
United States
janice
The price is AED 446
AED 577 total
includes taxes & fees
9 Aug - 10 Aug
Hotel Indigo Mount Pleasant by IHG
Lobby

Sleep Inn Mt. Pleasant - Charleston

Sleep Inn Mt. Pleasant - Charleston
2.5 star property
Mount Pleasant
7.8 out of 10, Good, (1,000 reviews)
"Room was clean staff was friendly"
United States
Ashley
The price is AED 360
AED 415 total
includes taxes & fees
21 Jul - 22 Jul
Sleep Inn Mt. Pleasant - Charleston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Mount Pleasant Hotel Reviews

Emeline

Emeline

10/10 Excellent
"We stayed at Hotel Emeline to celebrate our anniversary, and it exceeded every expectation. The hotel is beautiful, impeccably clean, and perfectly located for exploring Charleston on foot. Our room was elegant, the bathroom was gorgeous (even down to the Kohler fixtures), and the bed was one of the most comfortable we’ve ever slept in—we looked forward to coming back to it every evening after exploring the city. What truly sets this hotel apart, though, is the people. Every employee we encountered embodied genuine Southern hospitality. From the thoughtful check-in experience to the friendly housekeeping staff and bartenders who made us feel like regulars, the service was consistently exceptional. The hotel even provides thoughtful touches like complimentary reusable glass water bottles for guests to take while exploring the city and drink vouchers for their sister property. The moment that made us lifelong fans happened after checkout. I accidentally left my jacket in the lobby and didn’t realize it until we were already at the airport. We called expecting to pay to have it shipped home, but instead, a staff member personally drove my jacket to the airport—nearly a 30-minute drive—so I could have it before our flight. She even refused to accept a tip. That level of kindness and care is something you simply don’t see anymore. Hotel Emeline made our anniversary feel truly special, and we’ll absolutely stay here again the next time we’re in Charleston."
Sherry 3-night trip
Posted 2 hours ago
Emeline

Explore a world of travel with Expedia