The Best Business Hotels in Mount Pleasant, SC from AED 371 in 2026

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Our top choices for Mount Pleasant business-friendly hotels

A modern bar area with a wooden ceiling, bar stools, and a counter.

1. Cambria Hotel Mount Pleasant – Charleston

Mount Pleasant

william

AED 442 total

includes taxes & fees

22 Nov - 23 Nov

A swimming pool with lounge chairs and umbrellas, surrounded by trees and a building with multiple windows.

2. Holiday Inn Express & Suites Mt. Pleasant by IHG

Mount Pleasant

Naomi

AED 428 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with a high ceiling, a mezzanine level, and multiple seating areas including sofas and chairs.

3. Comfort Inn & Suites Patriots Point

Mount Pleasant

Trevor

AED 420 total

includes taxes & fees

22 Nov - 23 Nov

Two fishing boats docked at a pier with calm water and a clear sky.

4. Shem Creek Inn

Mount Pleasant

Derek

AED 633 total

includes taxes & fees

15 Nov - 16 Nov

A spacious lounge area with a stone accent wall, a flat-screen TV, multiple seating options including sofas and chairs, and a patterned carpet.

5. Staybridge Suites Charleston - Mount Pleasant by IHG

Mount Pleasant

Janice

AED 568 total

includes taxes & fees

22 Nov - 23 Nov

A modern bar area with wooden bar stools, pendant lighting, and a large window offering a view of the outdoors.

6. Hampton Inn Charleston/Mount Pleasant-Patriots Point

Mount Pleasant

Kelly

AED 446 total

includes taxes & fees

22 Nov - 23 Nov

A hotel lobby with seating areas, a reception desk, and decorative lighting.

7. Tru by Hilton Mt Pleasant Charleston

Mount Pleasant

Pamela

AED 427 total

includes taxes & fees

23 Nov - 24 Nov

A modern hotel lobby with a dining area, a bar, and a television.

8. Springhill Suites by Marriott Charleston Mount Pleasant

Mount Pleasant

Angela

AED 447 total

includes taxes & fees

22 Nov - 23 Nov

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Top Mount Pleasant Hotel Reviews

Hampton Inn Charleston/Mount Pleasant-Patriots Point

10/10 Excellent

"We stayed here for a quick weekend visit. The bed was great. Bathroom a little small. Location - easy to get to Charleston and close to some great Mt. Pleasant restaurants. Christine at front desk gave us great recommendations and told us how to sync Lyft to our Hilton account. Very helpful!"

Quality Inn Mt. Pleasant - Charleston

8/10 Good

"Our stay at this hotel was better than most of the other places we have stayed in Mount Pleasant be. Bed was very comfortable. The bedroom area was clean. The staff was friendly and helpful. The breakfast better than most that some other hotels of the dame caliber offer. My only negative comments was the toilet. Which, for short people and was uncomfortable for my husband. The tub had considerable rust by the front area faucet and on the floor where the tub and floor connected was pretty yucky ( for lack of a better word) these were maintenance issues not housekeeping. And finally every time we tried to get ice from the macine there was none. We would not hesitate to stay again."

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Our top choices for Mount Pleasant business-friendly hotels

1. Cambria Hotel Mount Pleasant – Charleston