The Best Business Hotels in Mount Pleasant, SC from AED 371 in 2026

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Our top choices for Mount Pleasant business-friendly hotels

A modern bar area with a wooden ceiling, bar stools, and a counter.

1. Cambria Hotel Mount Pleasant – Charleston

Mount Pleasant

william

AED 442 total

includes taxes & fees

22 Nov - 23 Nov

A swimming pool with lounge chairs and umbrellas, surrounded by trees and a building with multiple windows.

2. Holiday Inn Express & Suites Mt. Pleasant by IHG

Mount Pleasant

Naomi

AED 428 total

includes taxes & fees

1 Nov - 2 Nov

Two fishing boats docked at a pier with calm water and a clear sky.

3. Shem Creek Inn

Mount Pleasant

Derek

AED 627 total

includes taxes & fees

15 Nov - 16 Nov

A spacious lobby with a high ceiling, a mezzanine level, and multiple seating areas including sofas and chairs.

4. Comfort Inn & Suites Patriots Point

Mount Pleasant

Trevor

AED 410 total

includes taxes & fees

23 Nov - 24 Nov

A spacious lounge area with a stone accent wall, a flat-screen TV, multiple seating options including sofas and chairs, and a patterned carpet.

5. Staybridge Suites Charleston - Mount Pleasant by IHG

Mount Pleasant

Janice

AED 568 total

includes taxes & fees

22 Nov - 23 Nov

A modern bar area with wooden bar stools, pendant lighting, and a large window offering a view of the outdoors.

6. Hampton Inn Charleston/Mount Pleasant-Patriots Point

Mount Pleasant

Kelly

AED 446 total

includes taxes & fees

22 Nov - 23 Nov

A hotel lobby with seating areas, a reception desk, and decorative lighting.

7. Tru by Hilton Mt Pleasant Charleston

Mount Pleasant

Pamela

AED 427 total

includes taxes & fees

23 Nov - 24 Nov

A covered outdoor area with a pool, palm trees, and lounge chairs.

8. The Beach Club at Charleston Harbor Resort and Marina

Mount Pleasant

Robert

AED 881 total

includes taxes & fees

23 Nov - 24 Nov

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Top Mount Pleasant Hotel Reviews

Extended Stay America Suites Charleston Mt Pleasant

8/10 Good

"Front counter person was friendly and helpful"

Holiday Inn Express & Suites Mt. Pleasant by IHG

10/10 Excellent

"We were pleasantly surprised by the excellence of the Holiday Inn Express we stayed at in Mt. Pleasant, SC. The room was updated and very clean and comfortable. The coffee was available 24/7 from a single serve fresh bean coffeemaker and was the best from most hotels we've stayed at. There was a steady supply of water with fresh oranges. Staff was pleasant and made sure we had the amenities we wanted. We had a room next to the elevator but never heard it operating. Ample parking outside was an extra $5/day but worth it to make sure it was for patrons only. The hotel was conveniently located for seeing all the sites including downtown Charleston with only a short drive. We highly recommend this hotel."

Sleep Inn Mt. Pleasant - Charleston

10/10 Excellent

"Stayed here during a 4-day trip with my boyfriend. Everything was great especially for the price. The fact that breakfast and parking are included is a major plus. The beds were really comfy and I appreciated all the pillows on the bed. Rarely do I find pillows in hotels that are just right. The hotel’s surroundings are very quiet and tranquil, which is something I appreciated as a light sleeper. We had a rental to help us get around. There is a lot to see in Mt. Pleasant! There are so many great food spots near the hotel and it’s only about a 15-min drive to downtown Charleston where you’ll find even more great places to eat and visit. Overall, staying here was a great choice because we were able to stretch our vacation budget and had a wonderful time!"

Hampton Inn Charleston/Mount Pleasant-Patriots Point

10/10 Excellent

"We stayed here for a quick weekend visit. The bed was great. Bathroom a little small. Location - easy to get to Charleston and close to some great Mt. Pleasant restaurants. Christine at front desk gave us great recommendations and told us how to sync Lyft to our Hilton account. Very helpful!"

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Our top choices for Mount Pleasant business-friendly hotels

1. Cambria Hotel Mount Pleasant – Charleston