A pier extending into calm waters at sunset with a pink and blue sky.

Find Resorts & Hotels with Spas in Isle of Palms, SC

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Isle of Palms Resorts & Hotels with Spas

Next weekend
3 Jul - 5 Jul
In two weeks
10 Jul - 12 Jul

Our top choices for Isle of Palms hotels with a spa

Lobby

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn
4.0 star property
Isle of Palms
8.8 out of 10, Excellent, (1,003 reviews)
  • cleanliness
    Discover a coastal wellness haven with 14 treatment rooms, heated pools, and serene spa experiences for an unforgettable retreat.
The price is AED 1,216
AED 1,625 total
includes taxes & fees
6 Jul - 7 Jul
Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn
Interior

Wild Dunes Resort – Residences at Sweetgrass

Wild Dunes Resort – Residences at Sweetgrass
3.5 star property
Isle of Palms
8.6 out of 10, Excellent, (201 reviews)
  • cleanliness
    Rejuvenate at this coastal retreat with a full-service spa offering deep-tissue massages, body wraps, and facials for ultimate relaxation.
The price is AED 1,286
AED 1,717 total
includes taxes & fees
10 Jul - 11 Jul
Wild Dunes Resort – Residences at Sweetgrass
Couples treatment rooms, hot stone massages, deep-tissue massages

Harborside at Charleston Harbor Resort and Marina

Harborside at Charleston Harbor Resort and Marina
4.0 star property
Mount Pleasant
8.6 out of 10, Excellent, (2,150 reviews)
  • cleanliness
    Discover a waterfront wellness haven with tranquil spa treatments, couples massage rooms, and stunning sunset views from hot tubs.
The price is AED 528
AED 771 total
includes taxes & fees
30 Jun - 1 Jul
Harborside at Charleston Harbor Resort and Marina
Couples treatment rooms, sauna, steam room, body treatments

The Cooper

The Cooper
5.0 star property
Charleston Historic District
10.0 out of 10, Exceptional, (5 reviews)
The price is AED 2,696
AED 3,312 total
includes taxes & fees
6 Jul - 7 Jul
The Cooper
2 outdoor pools, free cabanas, pool umbrellas

The Beach Club at Charleston Harbor Resort and Marina

The Beach Club at Charleston Harbor Resort and Marina
4.5 star property
Mount Pleasant
9.2 out of 10, Wonderful, (1,022 reviews)
  • cleanliness
    Retreat to this harborside haven with couples spa treatments and a heated pool, perfect for unwinding amid beautiful marina views.
The price is AED 823
AED 1,104 total
includes taxes & fees
1 Jul - 2 Jul
The Beach Club at Charleston Harbor Resort and Marina
Spa

The Birdhouse Pet friendly 2 Bed With Yard And Hot Tub

The Birdhouse Pet friendly 2 Bed With Yard And Hot Tub
West Ashley
9.4 out of 10, Exceptional, (48 reviews)
  • cleanliness
    Relaxing retreat with private hot tub and massage services in a pet-friendly apartment near College of Charleston.
The price is AED 713
AED 1,123 total
includes taxes & fees
14 Jul - 15 Jul
The Birdhouse Pet friendly 2 Bed With Yard And Hot Tub
Reception

The Pinch Hotel

The Pinch Hotel
4.0 star property
Charleston Historic District
9.8 out of 10, Exceptional, (199 reviews)
  • cleanliness
    Immerse in serene spa treatments at this Charleston hotel with couples' massage rooms and a cozy fireplace lobby.
The price is AED 1,021
AED 1,290 total
includes taxes & fees
6 Jul - 7 Jul
The Pinch Hotel
Gift shop

Hotel Bennett

Hotel Bennett
5.0 star property
Charleston Historic District
9.6 out of 10, Exceptional, (1,001 reviews)
  • cleanliness
    Relax in elegance at this Charleston hotel with a full-service spa, rooftop pool, and 5 treatment rooms.
The price is AED 1,612
AED 1,847 total
includes taxes & fees
1 Jul - 2 Jul
Hotel Bennett
Check-in/check-out kiosk

The Dewberry Charleston

The Dewberry Charleston
5.0 star property
Charleston Historic District
9.6 out of 10, Exceptional, (1,003 reviews)
  • cleanliness
    Indulge in a tranquil spa retreat at this Charleston hotel where 5 treatment rooms offer deep-tissue massages and body wraps.
The price is AED 1,208
AED 1,386 total
includes taxes & fees
12 Jul - 13 Jul
The Dewberry Charleston
Couples treatment rooms, body treatments, aromatherapy

Wentworth Mansion

Wentworth Mansion
5.0 star property
Downtown Charleston
10.0 out of 10, Exceptional, (160 reviews)
  • cleanliness
    Revive at this Charleston boutique gem with private spa suites for couples and therapeutic garden-view massage treatments.
The price is AED 1,454
AED 1,668 total
includes taxes & fees
6 Jul - 7 Jul
Wentworth Mansion
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Choose what matters most at spa hotels in Isle of Palms

Pool
Breakfast included

Top Isle of Palms Hotel Reviews

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

10/10 Excellent
"We truly enjoyed our stay. All the staff were so accommodating and friendly. We will definitely go back!"
Kathryn M. 4-night trip
Posted 2 days ago
Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

Explore a world of travel with Expedia

Frequently asked questions

Looking to vacation at a spa hotel in Isle of Palms?
Forget the stress of everyday life and book yourself a hotel with a spa. Travelers love the beaches in Isle of Palms. Enjoy the live music and many popular restaurants during your vacation. Spa hotels are a great way to take a break from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Isle of Palms?
Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn is a top beach spa hotel featuring 5 pools, 8 restaurants, 9 bars, and a golf course. Enjoy a facial, body scrub, or detox wrap at The Spa at Sweetgrass. Another popular spa hotel in Isle of Palms is Wild Dunes Resort – Residences at Sweetgrass.
How many spa hotels will I find in Isle of Palms?
Among Expedia's 1731 accommodation options in Isle of Palms, there are 2 spa hotels.
What's there to see and do in Isle of Palms?
Enjoy all that Isle of Palms has to offer and visit Isle of Palms County Park, Isle of Palms Beach, and Isle of Palms Marina. If you have some spare time during your trip, you might want to check out Front Beach and Wild Dunes Resort Golf Course.
What is a Isle of Palms spa hotel?
Spa hotels in Isle of Palms provide lodging and have a full on-site spa which offers services like couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.