Photo by Jessica Richter
Find Family Hotels in Southeast Missouri, MO
- Be pickySearch almost a million properties worldwide
- Change your mindBook hotels with free cancellation
Plan, book, stay with confidence
Check availability on Southeast Missouri Family Hotels
Pick from 60 Southeast Missouri Family Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MO
9.6 out of 10, Exceptional, (960)
The price is AED 397
AED 419 total
includes taxes & fees
28 May - 29 May
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
9.6 out of 10, Exceptional, (1002)
The price is AED 430
AED 480 total
includes taxes & fees
29 May - 30 May
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
9.4 out of 10, Exceptional, (1000)
The price is AED 364
AED 413 total
includes taxes & fees
9 Jun - 10 Jun
Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
9.4 out of 10, Exceptional, (1002)
The price is AED 347
AED 397 total
includes taxes & fees
27 May - 28 May
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
9.4 out of 10, Exceptional, (786)
The price is AED 397
AED 447 total
includes taxes & fees
28 May - 29 May
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS, an IHG Hotel
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS, an IHG Hotel
9.4 out of 10, Exceptional, (556)
The price is AED 463
AED 521 total
includes taxes & fees
28 May - 29 May
Drury Inn & Suites Hayti Caruthersville
Drury Inn & Suites Hayti Caruthersville
9.4 out of 10, Exceptional, (993)
The price is AED 446
AED 509 total
includes taxes & fees
28 May - 29 May
Auburn Place Hotel And Suites
Auburn Place Hotel And Suites
8.8 out of 10, Excellent, (1004)
The price is AED 290
AED 321 total
includes taxes & fees
26 May - 27 May
Best Western Plus Sikeston
Best Western Plus Sikeston
8.4 out of 10, Very Good, (1002)
The price is AED 370
AED 413 total
includes taxes & fees
26 May - 27 May
Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape Girardeau
8.2 out of 10, Very Good, (640)
The price is AED 360
AED 390 total
includes taxes & fees
2 Jun - 3 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent reviews of Southeast Missouri hotelsExpedia verified reviews
5/5 Excellent
"Great value and super quiet. "
A verified traveler stayed at Days Inn and Suites by Wyndham Sikeston
Posted 12 hours ago
Find More Hotels near Southeast Missouri
More Hotel Options in Southeast Missouri
- Adventure Hotels (17)
- Business Hotels (50)
- Casinos (13)
- Cheap Hotels (23)
- Golf Hotels (28)
- Historic Hotels (10)
- Hotel Wedding Venues (16)
- Hotel with a Concierge (2)
- Hotels with Bars (19)
- Hotels with Free Parking (65)
- Hotels with Hot Tubs (22)
- Hotels with Waterslides (1)
- Hotels with WiFi (67)
- Hotels with a Pool (45)
- Hotels with an Indoor Pool (26)
- Hotels with smoking rooms (9)
- Luxury Hotels (12)
- Pet-friendly Hotels (48)
- Resorts & Hotels with Spas (14)
- Romantic Hotels (5)
- Shopping Hotels (29)
- Ski Hotels (1)
- Winery Hotels (7)
More Accommodation Types in Southeast Missouri
- Vacation Homes in Missouri (4,437)
- Condo Rentals in Missouri (4,433)
- Apartments in Missouri (2,206)
- Cabin Rentals in Missouri (1,195)
- Cottages in Missouri (670)
- Motels in Missouri (219)
- Resorts in Missouri (177)
- Lodges in Missouri (134)
- Chalets in Missouri (125)
- Villas in Missouri (103)
- B&B in Missouri (79)
- Farmstay in Missouri (65)
- Guest Houses in Missouri (59)
- RV Parks in Missouri (44)
- Aparthotels in Missouri (34)
- Inns in Missouri (7)
- Condo Resorts in Missouri (2)
- Hostels in Missouri (2)
- Town Houses in Missouri (2)
- Houseboats in Missouri (1)
- Residences in Missouri (1)
Hotels near popular Southeast Missouri Attractions
- Hotels near Johnson's Shut-ins State Park
- Hotels near Elephant Rocks State Park
- Hotels near Echo Bluff State Park
- Hotels near Lake Wappapello
- Hotels near Southeast Missouri State University
- Hotels near Ozark National Scenic Riverways
- Hotels near Big Spring
- Hotels near Century Casino Caruthersville
- Hotels near Alley Spring & Mill
- Hotels near Isle Casino Cape Girardeau
Southeast Missouri Hotels by Star Rating
Explore more hotels
- Pear Tree Inn Cape Girardeau Near the Medical Center
- Silo Farm Haus- located in the heart of wine country!
- Pear Tree Inn Sikeston
- Super 8 by Wyndham Farmington
- Candlewood Suites Cape Girardeau, an IHG Hotel
- Fairfield Inn & Suites by Marriott Poplar Bluff
- Comfort Inn Festus - St Louis South
- Quality Inn
- Super 8 by Wyndham Perryville
- Courtyard by Marriott Cape Girardeau Downtown
- The Farmstead Hotel
- La Quinta Inn & Suites by Wyndham Festus - St. Louis South
- Best Western Plus Sikeston
- Holiday Inn Express & Suites Perryville, an IHG Hotel
- Drury Inn & Suites Hayti Caruthersville
- Travel Inn & Suites
- Hampton Inn Poplar Bluff
- New Orleans Inn Portageville
- Drury Inn & Suites Poplar Bluff
- Comfort Suites Jackson-Cape Girardeau