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Find hotels in Southeast Missouri, MO from AEDĀ 230

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Our top choices for Southeast Missouri hotels

1. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,005 reviews)
"This hotel was so clean and comfy! The breakfast was awesome too!"
United States
Jamie
The price is AEDĀ 297
AEDĀ 315 total
includes taxes & fees
16 Aug - 17 Aug
Drury Inn & Suites Jackson MO

2. Shepherd Mountain Inn

Shepherd Mountain Inn
2.5 star property
Ironton
9.2 out of 10, Wonderful, (325 reviews)
"This was the perfect little place for my husband and I to stay for our little vacation. Very quiet, close to many state parks and beautiful scenery. The staff was friendly, the room was clean and organized, and the breakfast was very good. We will definitely stay there again next time we are in the area."
United States
Katie
The price is AEDĀ 453
AEDĀ 495 total
includes taxes & fees
6 Aug - 7 Aug
Shepherd Mountain Inn

3. Fort Davidson Hotel

Fort Davidson Hotel
2.5 star property
Ironton
9.2 out of 10, Wonderful, (185 reviews)
"We really enjoyed our stay. It was located near everything we wanted to do in that area. It is not a new location, but it was a good value. We would stay there again."
United States
John
The price is AEDĀ 459
AEDĀ 502 total
includes taxes & fees
10 Aug - 11 Aug
Fort Davidson Hotel

4. Madison Inn Lodge

Madison Inn Lodge
2.5 star property
Fredericktown
7.6 out of 10, Good, (305 reviews)
"The owner of this place was extremely nice. So was the cleaning staff. I would definitely stay here again."
United States
Christine
The price is AEDĀ 321
AEDĀ 351 total
includes taxes & fees
11 Aug - 12 Aug
Madison Inn Lodge

5. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,008 reviews)
"Staff was great"
United States
Paul
The price is AEDĀ 367
AEDĀ 414 total
includes taxes & fees
9 Aug - 10 Aug
Drury Plaza Hotel Cape Girardeau Conference Center

6. Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (911 reviews)
"Great overnight restful stay"
United States
Philip
The price is AEDĀ 343
AEDĀ 384 total
includes taxes & fees
23 Aug - 24 Aug
Hampton Inn Poplar Bluff

7. Crown Pointe Lodge, BW Signature Collection

Crown Pointe Lodge, BW Signature Collection
2.5 star property
Farmington
9.0 out of 10, Wonderful, (660 reviews)
"Very pretty area, staff was wonderful and breakfast was great slso!"
United States
Louise
The price is AEDĀ 403
AEDĀ 438 total
includes taxes & fees
30 Aug - 31 Aug
Crown Pointe Lodge, BW Signature Collection

8. Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
3.0 star property
Poplar Bluff
9.4 out of 10, Exceptional, (945 reviews)
"Nice clean area and motel."
United States
Jean
The price is AEDĀ 372
AEDĀ 420 total
includes taxes & fees
23 Aug - 24 Aug
Fairfield Inn & Suites by Marriott Poplar Bluff

9. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (215 reviews)
"The staff at breakfast was wonderful!"
United States
Heather
The price is AEDĀ 340
AEDĀ 384 total
includes taxes & fees
9 Aug - 10 Aug
Fairfield Inn & Suites by Marriott Cape Girardeau

10. Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.8 out of 10, Excellent, (490 reviews)
"Very clean room breakfast was good"
United States
michael
The price is AEDĀ 367
AEDĀ 416 total
includes taxes & fees
23 Aug - 24 Aug
Holiday Inn Express & Suites Sikeston Southwest by IHG

11. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.6 out of 10, Exceptional, (1,006 reviews)
"Nice hotel with evening dinner and buffet breakfast."
United States
Sally
The price is AEDĀ 408
AEDĀ 469 total
includes taxes & fees
9 Aug - 10 Aug
Drury Inn & Suites Sikeston, MO

12. Black River Motel and Restaurant

Black River Motel and Restaurant
2.0 star property
Lesterville
8.6 out of 10, Excellent, (45 reviews)
"Staff was very helpful and friendly"
United States
Douglas
The price is AEDĀ 426
AEDĀ 451 total
includes taxes & fees
6 Aug - 7 Aug
Black River Motel and Restaurant

13. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.4 out of 10, Exceptional, (105 reviews)
"Nice place to stay"
United States
JANEEN
The price is AEDĀ 284
AEDĀ 309 total
includes taxes & fees
9 Aug - 10 Aug
EC Reed's Mercantile and Hotel

14. Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington
2.0 star property
Farmington
8.0 out of 10, Very Good, (666 reviews)
"Will stay here when I return"
United States
Sarah
The price is AEDĀ 219
AEDĀ 238 total
includes taxes & fees
12 Aug - 13 Aug
Super 8 by Wyndham Farmington

15. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (160 reviews)
"Room was clean and staff were very friendly and helpful!"
United States
Gwendolyn
The price is AEDĀ 328
AEDĀ 374 total
includes taxes & fees
16 Aug - 17 Aug
Tru By Hilton Cape Girardeau

16. Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
2.5 star property
Farmington
8.0 out of 10, Very Good, (1,008 reviews)
"Great place"
United States
Kellie
The price is AEDĀ 212
AEDĀ 230 total
includes taxes & fees
17 Aug - 18 Aug
Baymont Inn and Suites by Wyndham Farmington, MO

17. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (537 reviews)
"Very conveniently located."
United States
Renee
The price is AEDĀ 459
AEDĀ 521 total
includes taxes & fees
15 Aug - 16 Aug
Courtyard by Marriott Cape Girardeau Downtown

18. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1,009 reviews)
"This was a very clean motel and had an excellent breakfast! Will stay there again!"
United States
Bonnie
The price is AEDĀ 264
AEDĀ 298 total
includes taxes & fees
9 Aug - 10 Aug
Pear Tree Inn Cape Girardeau West

19. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (101 reviews)
"Perfect last minute stop on our road trip Very clean, well maintained and pleasant staff"
United States
Dwain
The price is AEDĀ 404
AEDĀ 457 total
includes taxes & fees
13 Aug - 14 Aug
Fairfield Inn & Suites by Marriott Sikeston

20. Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
2.5 star property
Perryville
9.2 out of 10, Wonderful, (611 reviews)
"Nice"
United States
Jacalyn
The price is AEDĀ 364
AEDĀ 416 total
includes taxes & fees
3 Sep - 4 Sep
Holiday Inn Express & Suites Perryville by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Vacation Rentals in Southeast Missouri

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Stay near popular Southeast Missouri attractions

Learn more about Southeast Missouri

Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from Crane Lake Recreation Area to K Bridge Recreation Area.

A historical marker sign for the Frisco Depot, detailing its construction in 1928, architectural style, and historical significance.
Photo by Bill Dillard
Open Photo by Bill Dillard

Top Southeast Missouri Hotel Reviews

More cheap stays in Southeast Missouri

Hotels in Southeast Missouri with star-rating

Find out more about Southeast Missouri

Top reasons to visit Southeast Missouri

  • Outdoor Adventures: Southeast Missouri is perfect for outdoor enthusiasts, offering hiking, scenic retreats, and recreational activities.
  • Family-Friendly Experiences: The region provides numerous activities suitable for families, ensuring fun for all ages.
  • Cultural Attractions: Explore historic civic buildings and nearby sites, including Southeast Missouri State University.
  • Inviting Parks: Enjoy picturesque urban and state parks for leisurely strolls and nature exploration.
  • Diverse Accommodations: Choose from a range of lodging options, from cozy motels to well-equipped hotels to fit any traveler’s needs.

Find great hotels near Southeast Missouri

Explore the diverse hotel accommodations in Southeast Missouri, where options range from cozy motels to well-equipped hotels tailored for business travelers and adventure seekers alike. Whether you're looking for pet-friendly places or the best-reviewed stays, this region offers a variety of choices to suit every traveler's needs. Discover the perfect lodging to make your visit memorable, conveniently located near popular attractions and activities.

  • Madison Inn Lodge: Ideal for pet lovers and business travelers, Madison Inn Lodge is a welcoming motel located 25.7km from Southeast Missouri. This lodge embraces a pet-friendly atmosphere, allowing guests to bring their furry companions along for the adventure. Offering essential amenities like complimentary Wi-Fi and comfortable accommodations, it ensures a hassle-free stay. The property also features a welcoming environment for service animals, making it a perfect choice for those traveling for work or leisure with pets in tow.
  • Shepherd Mountain Inn: Located 33.8km from Southeast Missouri, Shepherd Mountain Inn stands out as a reliable choice for business travelers. This hotel provides a focused and comfortable environment, making it easy for guests to unwind or catch up on work. With modern amenities and convenient services, it caters to the needs of professionals seeking a productive stay. The inn's strategic location allows easy access to nearby business hubs and local attractions, ensuring that guests can balance work and leisure seamlessly.
  • Alpaca Farm Stay: For those yearning for adventure or a romantic getaway, Alpaca Farm Stay is a charming lodge just 12.9km away from Southeast Missouri. Nestled in nature, it offers various outdoor activities including mountain biking, kayaking, and hiking, catering to families and thrill-seekers alike. With amenities designed for children, such as a shared playground, it’s perfect for family vacations. Guests can also enjoy stunning views of the lake and mountains while indulging in romance packages, creating unforgettable memories amidst beautiful surroundings.

Where to stay near Southeast Missouri

Southeast Missouri offers an inviting blend of outdoor adventures and family-friendly experiences. Enjoy leisurely strolls through picturesque parks, or embark on scenic retreats to explore lush landscapes. With friendly locals and convenient access to attractions, visitors can indulge in recreational activities suitable for all ages. Don’t miss the chance to soak in the region's vibrant atmosphere during its wettest month, making it an unforgettable getaway for nature lovers and families alike.

  • Annapolis: Located 22.5km from Southeast Missouri, Annapolis is a charming city that attracts visitors year-round, especially during the warmer months of June to July and September. Known for its outdoor adventures and scenic beauty, this city offers a variety of recreational areas and an entertainment arena. Nature lovers will appreciate the proximity to a national state park, rivers, and picturesque parks, making Annapolis an ideal spot for those seeking adventure and outdoor experiences.
  • Central Fredericktown: Just 16.1km from Southeast Missouri, Central Fredericktown is a quaint village that draws family-oriented travelers looking for a city-themed experience. The peak travel times from June to August make it a lively destination during the summer months. Visitors can enjoy educational venues, shopping mall centers, and urban parks. The local history museum provides a glimpse into the region's past, while the various parks offer a relaxing escape for families and outdoor enthusiasts alike.
  • Des Arc: A mere 17.7km from Southeast Missouri, Des Arc is a vibrant city known for its seasonal influx of visitors, peaking from June to August. This city is perfect for those who enjoy outdoor activities and stunning scenery. Des Arc features an array of recreational areas, a water park, and an entertainment arena, ensuring fun for all ages. Outdoor enthusiasts will love the nearby national state park, lake, and rivers, making it a fantastic destination for adventure seekers and nature lovers.

Things to do near Southeast Missouri

Southeast Missouri is perfect for outdoor enthusiasts and adventure seekers, offering a variety of activities. Visitors can enjoy campus tours, outdoor sports tournaments, and brewery tours. The region also boasts recreational areas and educational experiences, making it an ideal destination for those looking to explore nature and engage in fun activities. Whether you're interested in sports or learning, there's something for everyone in Southeast Missouri.

Shopping

Experience shopping at Red's Flea Market, located 41.8km from Southeast Missouri, where you'll find a variety of unique gifts and treasures. Additionally, visit the Farmington Mineral Area Shopping Center, 48.3km away, offering a mix of family-friendly entertainment, shops, and dining options.

Recreation

Crane Lake Recreation Area offers a peaceful retreat with serene surroundings, perfect for relaxation and rejuvenation. Arcadia Valley Golf Club provides an invigorating outdoor experience with its scenic golf course. Silver Mine Recreation Area combines wellness and nature, featuring tranquil trails and beautiful landscapes for ultimate relaxation.

Adventure

Shepherd Mountain Bike Park and Hiking Trails offers thrilling outdoor adventures only 33.8km from Southeast Missouri. Experience scenic biking paths and hiking trails that wind through lush landscapes, perfect for both adrenaline seekers and nature lovers looking to immerse themselves in the beautiful surroundings.

Nightlife

Southeast Missouri's nightlife offers a mix of cozy bars and lively venues. Enjoy live music at The Blue Note in Columbia or sip craft beers at a local brewery. For dancing, head to The Parlor in Cape Girardeau, where vibrant crowds and energetic beats create an unforgettable atmosphere.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Southeast Missouri

To save money during your trip to Southeast Missouri, plan to visit between November and January, when accommodation prices are lower. Tuesdays are the cheapest days to book, while Saturdays tend to be the most expensive. Use Expedia's search tool to find budget-friendly hotels by sorting prices and applying filters for eco-certified options. Additionally, consider booking package deals that combine flights, hotels, and activities for extra savings. Take advantage of free local attractions and affordable public transport to explore the area without overspending.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Southeast Missouri are November to January, where the prices are slightly lower. This is in comparison to April, June and August, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Southeast Missouri is Tuesday. The most expensive day to stay around Southeast Missouri is Saturday.
  • Find cheap hotels on Expedia: Expedia's search tool enables you to set your budget, choose your desired location, and much more. You can organize your results to display prices from lowest to highest, ensuring you see the most affordable hotels first. Additionally, you have the option to narrow down your choices by hotel type. For instance, by selecting the Eco-certified filter, you'll find a selection of sustainable and environmentally-friendly hotels available for booking.
  • Consider bundling your trip: You can save money by combining your hotel reservations in Southeast Missouri with your flights and activities by choosing an Expedia package.

Find the best attractions near Southeast Missouri

Southeast Missouri offers a fantastic blend of outdoor adventures and scenic beauty, making it an ideal destination for families and nature lovers. Visitors can explore urban parks, state parks, and historic civic buildings. Notable attractions include nearby sites and Southeast Missouri State University, providing a mix of educational and recreational experiences. Whether you're hiking, sightseeing, or enjoying family-friendly activities, Southeast Missouri has something for everyone.

  • Walnut Hollow Lake: Nestled 20.9km away, Walnut Hollow Lake offers a serene escape with its picturesque beaches and stunning scenery. Ideal for a romantic day out or a peaceful retreat, this lake is perfect for swimming, picnicking, or simply enjoying the natural beauty.
  • K Bridge Recreation Area: Located 27.4km from Southeast Missouri, this urban park is a family-friendly destination featuring open spaces for picnics, walking trails, and playgrounds. It’s a great spot to unwind and enjoy the city vibes while spending quality time with loved ones.
  • Millstream Gardens Conservation Area: Just 24.1km away, this conservation area is rich in history and adventure. With friendly locals and relaxing trails, it’s ideal for families seeking outdoor fun, making it a perfect place to connect with nature and explore.

Best time to go to Southeast Missouri

The best time to visit Southeast Missouri can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around Southeast Missouri falls in July, when visitor numbers are slightly high and weather is mostly sunny with light rain. The coolest average temperature around Southeast Missouri falls in January, visitor numbers are slightly low and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January34.9°F (1.6°C)Light RainMostly SunnySlightly LowSlightly Low
February38.1°F (3.4000000000000004°C)Light RainMostly SunnySlightly LowAverage
March48.0°F (8.9°C)Light RainMostly SunnyAverageAverage
April57.6°F (14.2°C)Light RainMostly SunnyAverageSlightly High
May67.3°F (19.6°C)Light RainMostly SunnyAverageAverage
June76.5°F (24.700000000000003°C)Light RainMostly SunnySlightly HighSlightly High
July79.2°F (26.200000000000003°C)Light RainMostly SunnySlightly HighAverage
August77.2°F (25.1°C)Light RainMostly SunnySlightly HighSlightly High
September71.6°F (22.0°C)Light RainMostly SunnyAverageAverage
October59.9°F (15.5°C)Light RainMostly SunnyAverageAverage
November47.5°F (8.6°C)Light RainMostly SunnyAverageSlightly Low
December39.4°F (4.1000000000000005°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to Southeast Missouri

When visiting Southeast Missouri, you can fly into several major airports. St. Louis Lambert International Airport (STL) is located 154.5km away, with nearby hotels like The Ritz-Carlton and Ameristar Casino Resort, both about 11.3km from the airport. Fort Leonard Wood Regional Airport (TBN) is also 154.5km away, offering accommodations such as the Z Loft Extended Stay Hotel, just 9.7km from the airport. Additionally, Barkley Regional Airport (PAH) in Paducah, KY is 152.9km away, with options like The Respite Bed and Breakfast located 14.5km from the airport. Each of these airports provides accessible transport to nearby hotels for a convenient stay.

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