Find all hotels by Independent in Santee, SC
Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Compare rooms and suites by Independent in Santee with rates, reviews, and availability. Most hotels are fully refundable.
Recent reviews of Santee hotelsExpedia verified reviews
![Hampton Inn Santee-I-95](http://images.trvl-media.com/lodging/1000000/210000/203700/203667/c71aed2f_y.jpg)
Hampton Inn Santee-I-95
5/5 Excellent
"This Hampton Inn was beautiful, clean but the staff were the absolute best part about it! Front desk was so friendly, charming and kind! The wonderful ladies in charge of breakfast were so sweet and welcoming! We felt like we were dining at a restaurant.❤️😊 Would definitely recommend as a family friendly stop!"
A verified traveler stayed at Hampton Inn Santee-I-95
Posted 3 days ago
Santee Hotels by Brand
Hotels near popular Santee Attractions
- Hotels near Santee State Park
- Hotels near Santee Cooper Country Club
- Hotels near Santee Outlets
- Hotels near Santee National Golf Club
- Hotels near Congaree National Park
- Hotels near Lake Marion
- Hotels near South Carolina State University
- Hotels near Santee National Wildlife Refuge
- Hotels near Wyboo Golf Club
- Hotels near Edisto Memorial Gardens
More Hotel Options in Santee
- Adventure Hotels (3)
- Beach Hotels (1)
- Business Hotels (11)
- Cheap Hotels (7)
- Family Hotels (10)
- Golf Hotels (5)
- Hotel with a Concierge (1)
- Hotels with Bars (6)
- Hotels with Free Parking (11)
- Hotels with Hot Tubs (3)
- Hotels with WiFi (13)
- Hotels with a Pool (10)
- Hotels with an Indoor Pool (1)
- Hotels with smoking rooms (1)
- Luxury Hotels (5)
- Pet-friendly Hotels (10)
- Resorts & Hotels with Spas (2)
- Shopping Hotels (11)
Explore more hotels
- Super 8 by Wyndham Santee
- Two Palms Lakehouse in Santee Just minutes from I95
- Rodeway Inn Santee I-95
- Executive 2 BR/2 BA Lakefront Corner Suite Condo
- Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
- Waterfront 3 Bedroom / 3 Bath Condo w/ Boat Slip Available
- Wyndham Vacation Resorts Lake Marion
- Days Inn by Wyndham St George
- Tru by Hilton Orangeburg
- Country Inn & Suites by Radisson, Orangeburg, SC
- Fairfield Inn by Marriott Orangeburg
- SureStay Hotel by Best Western Manning
- SpringHill Suites by Marriott Orangeburg
- Travelodge by Wyndham Orangeburg
- Baymont by Wyndham Manning
- Hampton Inn Manning
- Baymont by Wyndham Orangeburg North
- Red Roof Inn St George, SC
- Holiday Inn Express & Suites Orangeburg
- Hampton Inn & Suites Orangeburg