Find hotels in Santo Spirito, Florence from AED 357

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Discover 470 Santo Spirito hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Horto Convento

4.0 star property
Santo Spirito
9.8 out of 10, Exceptional, (590)
"Excellent staff, so friendly and helpful. Lovely hotel in a great location. "
United Kingdom
Emma
The price is AED 351
AED 446 total
includes taxes & fees
9 Dec - 10 Dec
Hotel Horto Convento

Foresteria Valdese di Firenze - Casa per Ferie

Santo Spirito
8.8 out of 10, Excellent, (192)
"The staff was very helpful and room was clean "
United States
Cinda
Foresteria Valdese di Firenze - Casa per Ferie

Casa Santo Nome di Gesù

Santo Spirito
8.8 out of 10, Excellent, (337)
"I always enjoy my stay here. Nicely located, pleasant breakfast, terrific courtyard, nicely priced. "
United States
Marcie
The price is AED 434
AED 529 total
includes taxes & fees
18 Nov - 19 Nov
Casa Santo Nome di Gesù

Palazzo Mannaioni Suites

4.0 star property
Santo Spirito
9.2 out of 10, Wonderful, (1067)
"Clean and great staff"
United States
lauren
Palazzo Mannaioni Suites

Hotel Firenze 2000

2.0 star property
Santo Spirito
7.2 out of 10, Good, (189)
"The staff was wonderful and very helpful; 24 hr service ! The room was very clean and breakfast was plentiful. Great location if you don’t mind a short walk to the historic town center ; would definitely recommend."
Canada
Josee
The price is AED 290
AED 357 total
includes taxes & fees
14 Dec - 15 Dec
Hotel Firenze 2000

La Torre Del Cestello

Santo Spirito
9.0 out of 10, Wonderful, (223)
"Great location and great rooms"
United States
David
The price is AED 282
AED 371 total
includes taxes & fees
1 Dec - 2 Dec
La Torre Del Cestello

Oltrarno Splendid

Santo Spirito
10.0 out of 10, Exceptional, (96)
"It was Wonderful!!!"
United States
MARGARITA
The price is AED 620
AED 742 total
includes taxes & fees
1 Dec - 2 Dec
Oltrarno Splendid

Palazzo D'Oltrarno - Residenza D'Epoca

Santo Spirito
9.4 out of 10, Exceptional, (46)
"Excellent place to stay!"
United States
Diane
The price is AED 442
AED 538 total
includes taxes & fees
24 Nov - 25 Nov
Palazzo D'Oltrarno - Residenza D'Epoca

Della Calza Spa & Foresteria

Santo Spirito
The price is AED 970
AED 1,118 total
includes taxes & fees
18 Nov - 19 Nov
Della Calza Spa & Foresteria

La Fonderia Firenze

Santo Spirito
9.6 out of 10, Exceptional, (172)
"Breakfast outside was lovely"
United States
Kenneth
The price is AED 344
AED 430 total
includes taxes & fees
18 Nov - 19 Nov
La Fonderia Firenze

Torre di Bellosguardo

4.0 star property
Santo Spirito
9.0 out of 10, Wonderful, (103)
"Beautiful property and wonderful staff."
United States
Brad
The price is AED 1,373
AED 1,570 total
includes taxes & fees
18 Nov - 19 Nov
Torre di Bellosguardo

AdAstra Suites

Santo Spirito
9.8 out of 10, Exceptional, (219)
"Staff was absolutely wonderful!!! "
United States
Trisha
The price is AED 584
AED 702 total
includes taxes & fees
23 Nov - 24 Nov
AdAstra Suites

Hotel Palazzo Guadagni

3.0 star property
Santo Spirito
9.0 out of 10, Wonderful, (200)
"Hotel Palazzo was stunning. I would definitely stay here again and I already can't wait to! The staff were so friendly and made you feel right at home. Everything was walking distance and the area was incredible!"
United States
Annyelis
The price is AED 673
AED 791 total
includes taxes & fees
23 Nov - 24 Nov
Hotel Palazzo Guadagni

Drom Florence Rooms & Apartments

Santo Spirito
9.8 out of 10, Exceptional, (134)
"Ver clean and quiet, wonderful stay."
United States
kevin
Drom Florence Rooms & Apartments

1900 Artevita

Santo Spirito
8.8 out of 10, Excellent, (176)
"This property is great and the manager is very kind and helpful."
United States
Elizabeth
The price is AED 301
AED 383 total
includes taxes & fees
18 Nov - 19 Nov
1900 Artevita

Hostel Santa Monaca

Santo Spirito
8.0 out of 10, Very Good, (60)
"I found it easy to move around and walked everywhere. Staff super friendly. Ten people in one room was a bit much, but overall comfortable. Thank you.!"
Canada
Alma
Hostel Santa Monaca

Residenza D'Epoca Al Numero 8

Santo Spirito
8.8 out of 10, Excellent, (137)
"Very nice place to stay. closed to good restaurantsand shopping. "
United States
JULIO
Residenza D'Epoca Al Numero 8

Ottantotto Firenze

Santo Spirito
9.6 out of 10, Exceptional, (169)
"Fabulous hotel , breakfast was amazing , great location "
United Kingdom
SAMANTHA
The price is AED 770
AED 907 total
includes taxes & fees
20 Nov - 21 Nov
Ottantotto Firenze

L'Antica Porta Boutique B&B

Santo Spirito
8.8 out of 10, Excellent, (18)
"Clean and comfy room | Easy transportation | Safe"
United States
Gabriel
The price is AED 318
AED 401 total
includes taxes & fees
18 Nov - 19 Nov
L'Antica Porta Boutique B&B

Soderini Apartments by MMega

Santo Spirito
9.6 out of 10, Exceptional, (7)
"Having laundry in the room was great! The location was nice. Easy to walk to tourist sites. Grocery store was almost next door. Gelato store was almost next door. All the bases were covered!"
Canada
Brett
The price is AED 244
AED 661 total
includes taxes & fees
23 Nov - 24 Nov
Soderini Apartments by MMega
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Santo Spirito with free breakfast

Hotels in Santo Spirito with a pool

Top guest rated hotels in Santo Spirito

Where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most.

Historic Centre of Florence

Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Via de' Calzaiuoli and Piazza della Repubblica are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

Duomo

Via de' Calzaiuoli and Giotto's Campanile are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. The New Florence Opera House is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

San Giovanni

If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

Santa Croce

Travelers come to Santa Croce for its interesting museums, and you can see top attractions like Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top Santo Spirito Hotel Reviews

Find out more about Santo Spirito

Top reasons to visit Santo Spirito

  • Vibrant Cultural Experience: Santo Spirito offers a unique blend of lively markets and artistic neighborhoods, perfect for immersing in local life.
  • Historic Architecture: Explore picturesque streets featuring stunning buildings and the iconic Pitti Palace.
  • Piazza Santo Spirito: Enjoy the romantic atmosphere of this charming square, a hub of local activity.
  • Artisan Workshops: Discover the Oltrarno district, known for its traditional craftsmanship and artisan shops.
  • Diverse Accommodations: Choose from a variety of hotels and cozy bed & breakfasts to suit every traveler's needs.

Where to stay near Santo Spirito

Discover the vibrant charm of Santo Spirito, Florence, where trendy cafes meet historical streets. Explore the artistic Oltrarno district, home to stunning artisan workshops and the iconic Pitti Palace. Wander through the picturesque streets to find the historic square, Piazza Santo Spirito, and indulge in the romantic atmosphere of this secluded neighborhood. Just a short distance away, visit charming villages that enhance the region's rich culture and history, making your vacation truly unforgettable.

  • Florence: As the heart of Tuscany, Florence is an enchanting city where art, culture, and history breathe life into every street corner. Known for its rich heritage, visitors flock to explore its iconic museums, historic piazzas, and bustling markets. The vibrant atmosphere peaks during spring and early fall, making it a perfect time to experience outdoor cafes and local shopping. Key landmarks such as the Uffizi Gallery and Ponte Vecchio are must-visit spots, drawing culture enthusiasts and outdoor lovers alike to immerse themselves in the Florentine spirit.
  • Historic Centre of Florence: Located just 1.6km from Santo Spirito, the Historic Centre of Florence is a UNESCO World Heritage site filled with stunning architecture and cultural treasures. This neighborhood sees an influx of visitors during the summer months, particularly for family-friendly events and theatrical performances. Wander through its charming streets to admire the historic bridges and lively piazzas, where you can enjoy outdoor dining and local art. The area serves as a fantastic hub for education and exploration, offering a glimpse into Florence's storied past.
  • Duomo: A mere 1.4km from Santo Spirito, the Duomo neighborhood is renowned for its breathtaking cathedral and vibrant urban life. Similar to its neighboring areas, it attracts visitors during the summer, making it a lively spot for families and culture seekers. The piazza is perfect for people-watching, while the nearby public markets present an opportunity to savor local delicacies. The historic bridges and proximity to key attractions ensure that you’ll find plenty to see and do in this picturesque area, making it an essential stop on your Florentine adventure.

Things to do near Santo Spirito

Santo Spirito offers a vibrant cultural experience, perfect for city and outdoor enthusiasts. Visitors can explore the lively public market and various shopping areas, immersing themselves in the local atmosphere. Don't miss the opportunity to join a photo tour, capturing the picturesque streets and stunning architecture that define this charming neighborhood of Florence, Tuscany.

Shopping

In Santo Spirito, enjoy the Central Market, a vibrant public market just 1.6km away, perfect for local goods. Visit Pitti Vintage, a charming store 966m away, or explore Mercato di Sant'Ambrogio, another bustling market located 3.2km from the area for unique souvenirs.

Recreation

Experience the vibrant atmosphere at Stadio Artemio Franchi, where you can enjoy various sports events. For relaxation, head to Nelson Mandela Forum, a serene space perfect for unwinding. Lastly, dive into family fun at Costoli Pool, featuring outdoor activities and sports vibes for everyone.

Adventure

Experience Fiesole Bike Day Tours for an exhilarating ride through scenic landscapes, located 1.6km from Santo Spirito. For thrill-seekers, Mugello Circuit offers exciting motor racing action, 27.4km away. Enjoy breathtaking views while hiking at Parco di Montececeri, situated 6.4km from Santo Spirito.

Nightlife

Experience the vibrant nightlife of Santo Spirito by visiting Teatro Verdi or Teatro della Pergola, both offering romantic cultural performances. For a family-friendly atmosphere, check out the Arcetri Observatory, where you can enjoy entertaining shows under the stars. Each venue promises a unique experience just 1.6km away.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions near Santo Spirito

Santo Spirito is perfect for culture and city-themed vacations, offering a rich blend of outdoor experiences. Key attractions include Santo Spirito Square and the local church, as well as various art museums. This vibrant area caters to travelers seeking cultural enrichment, family experiences, and the charm of a historic piazza. Whether you're exploring local art or enjoying the lively atmosphere, Santo Spirito promises an unforgettable visit in Florence, Tuscany.

  • Ponte Vecchio: Stroll across this historic bridge, renowned for its charming shops and stunning views of the Arno River. Ponte Vecchio is a vibrant cultural hub where you can soak in the rich history and admire the beautiful architecture.
  • Uffizi Gallery: Explore one of the world’s most famous art museums, home to masterpieces by Botticelli, Michelangelo, and da Vinci. The Uffizi Gallery offers a deep dive into Renaissance art and culture, making it a must-visit for art enthusiasts.
  • Cathedral of Santa Maria del Fiore: Marvel at the breathtaking façade and dome of Florence's iconic cathedral. This architectural masterpiece offers a glimpse into the city’s religious heritage and stunning views from its dome, enhancing your cultural experience.

The nearest major airports for your trip to Santo Spirito

Traveling to Santo Spirito in Florence, Tuscany, is convenient with several major airports nearby. Florence Airport (FLR-Peretola) is approximately 4.8km away, with luxurious hotel options like Palazzo Montebello and Hotel Lungarno, both offering transfer services. Bologna Airport (BLQ-Guglielmo Marconi) is about 54.8km distant, featuring hotels such as Grand Hotel Majestic già Baglioni, which provides shuttle services. Pisa Airport (PSA-Galileo Galilei) is around 67.6km from Santo Spirito, with nearby accommodations like Bagni di Pisa Palace & Thermal Spa, also offering transfers. Each location provides easy access to transportation options for a smooth journey to your destination.

Explore a world of travel with Expedia

Frequently asked questions

What is Santo Spirito like?
Santo Spirito is a trendy neighborhood known for its beautiful river views. Be sure to check out Porta Romana and Piazza Santo Spirito as part of your Santo Spirito travel plans.
What's the best accommodation in Santo Spirito?
Based on Expedia customer reviews, Oltrarno Splendid is the highest ranked property in Santo Spirito. This B&B is a short 7-minute walk from Piazza di Santa Maria Novella, and it offers free breakfast and free WiFi. Other favorite options in the area include SPIRIT OF FLORENCE Boutique Rooms and Ottantotto Firenze.
How many hotels can I expect to find in the Santo Spirito area?
Expedia has 478 hotels and other accommodations in Santo Spirito to choose from, making this an ideal home base for exploring the greater Florence area.
If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best deals in Santo Spirito.
Where can I learn more about changing or cancelling my trip to Santo Spirito?
To find more details about updating your trip to Santo Spirito or cancelling it, head over to our customer service page.
What can I see and do in this Florence neighborhood?
Spend some time exploring the natural setting of Santo Spirito with a visit to Arno River and Torrigiani Garden. As you're discovering the neighborhood, Porta Romana and Piazza Santo Spirito are some other places worth a visit. A few places to visit in the area around Santo Spirito include Piazza del Carmine, Santa Maria della Carmine, and Brancacci Chapel. When you're sightseeing in Florence, Il Nabucco di Matteo Gabellini and Teatro Comunale Florence are also worth a stop.