Find 4 Star Hotels in Panama City from AED 179

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Check availability on Panama City 4 Star Hotels

Tonight
3 Dec - 4 Dec
Tomorrow
4 Dec - 5 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Compare Panama City 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Outdoor pool, pool umbrellas, sun loungers
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4.0 star property
Tocumen
8.4 out of 10, Very Good, (2320)
"Spacious room, clean, good breakfast "
United States
Juan
The price is AED 379
AED 478 total
includes taxes & fees
11 Dec - 12 Dec
Crowne Plaza Panama Airport by IHG
Front of property
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 star property
San Francisco
8.4 out of 10, Very Good, (1243)
"Its a very beautiful hotel with view and very good breakfast "
United States
Patrick
The price is AED 508
AED 559 total
includes taxes & fees
23 Dec - 24 Dec
Megapolis Hotel Panamá
View from property
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1032)
"Wonderful stay!"
United States
Martha
The price is AED 561
AED 617 total
includes taxes & fees
17 Dec - 18 Dec
Las Americas Golden Tower Panama
Terrace/patio
Marriott Panama Hotel

Marriott Panama Hotel

4.0 star property
Panama City
9.0 out of 10, Wonderful, (1017)
"Great breakfast "
United States
Amina
The price is AED 521
AED 573 total
includes taxes & fees
7 Dec - 8 Dec
Marriott Panama Hotel
Front of property
Novotel Panama City

Novotel Panama City

4.0 star property
Bella Vista
9.2 out of 10, Wonderful, (1026)
"Room very clean, nice staffs and good location "
United States
Hayden
The price is AED 334
AED 367 total
includes taxes & fees
9 Dec - 10 Dec
Novotel Panama City
Restaurant
Studio Coliving

Studio Coliving

4.5 star property
Bella Vista
7.8 out of 10, Good, (574)
"The staff was friendly and always helpful when I had requests. The room was"
United States
Toni-Q
The price is AED 162
AED 179 total
includes taxes & fees
4 Dec - 5 Dec
Studio Coliving
Exterior
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4.0 star property
San Francisco
8.6 out of 10, Excellent, (1423)
"Good place for a short stay"
United States
carlos
Decapolis Hotel Panama City
Outdoor pool, pool umbrellas, sun loungers
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1112)
"Property and location was excellent. Staff is very accommodating and helpful. "
Canada
Helen
The price is AED 368
AED 404 total
includes taxes & fees
2 Jan - 3 January 2026
Ramada Plaza by Wyndham Panama Punta Pacifica
Front of property - evening/night
American Trade Hotel

American Trade Hotel

4.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (600)
"Excellent service and great rooms on a beautiful and historical building"
Canada
Manuel
The price is AED 1,190
AED 1,309 total
includes taxes & fees
8 Dec - 9 Dec
American Trade Hotel
Terrace/patio
Sheraton Grand Panama

Sheraton Grand Panama

4.0 star property
San Francisco
8.6 out of 10, Excellent, (987)
"Great staff. Great restaurants and bakery. "
United States
Duncan Eric
The price is AED 468
AED 515 total
includes taxes & fees
12 Dec - 13 Dec
Sheraton Grand Panama
Outdoor pool
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4.0 star property
Bella Vista
9.0 out of 10, Wonderful, (608)
"Friwndly staff, clean rooms and a very convenient location."
United States
Alisa
The price is AED 269
AED 400 total
includes taxes & fees
8 Dec - 9 Dec
Waymore Hotel Spa & Casino
Breakfast, lunch, dinner served; international cuisine
Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall

4.0 star property
Cerro Viento
8.8 out of 10, Excellent, (1018)
"Conveniently located near the airport and major shopping outlets."
United States
Greg
The price is AED 403
AED 443 total
includes taxes & fees
18 Dec - 19 Dec
Courtyard by Marriott Panama Metromall
Exterior
Holiday Inn Panama Distrito Financiero by IHG

Holiday Inn Panama Distrito Financiero by IHG

4.0 star property
Bella Vista
8.8 out of 10, Excellent, (1020)
"Clean room, staff in the restaurant and housekeeping very friendly"
United States
Carmen
The price is AED 262
AED 288 total
includes taxes & fees
7 Dec - 8 Dec
Holiday Inn Panama Distrito Financiero by IHG
47-inch flat-screen TV with cable channels, TV
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4.0 star property
Casco Viejo
9.0 out of 10, Wonderful, (1001)
"Hotel was beautiful, staff was very helpful and accommodating. We had the pool two separate days to ourselves. Breakfadt was very good. Staff was very helpful getting us drivers wherever we wanted to go in the city."
United States
MICHELE
Central Hotel Panama Casco Viejo
Exterior
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4.0 star property
San Francisco
8.8 out of 10, Excellent, (1000)
"Perfect stay "
United States
pedro
The price is AED 434
AED 477 total
includes taxes & fees
13 Dec - 14 Dec
Courtyard by Marriott Panama Multiplaza Mall
Outdoor pool, open 6:00 AM to 11:00 PM, pool umbrellas, sun loungers
Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City

4.0 star property
San Francisco
9.0 out of 10, Wonderful, (534)
"Amazing hotel amazing view service great location perfect "
United States
Melissa
The price is AED 528
AED 580 total
includes taxes & fees
3 Jan - 4 January 2026
Residence Inn by Marriott Panama City
Restaurant
Hyatt Regency Panama City

Hyatt Regency Panama City

4.5 star property
Bella Vista
10.0 out of 10, Exceptional, (115)
"Great hotel fair price"
United States
Santiago
The price is AED 463
AED 509 total
includes taxes & fees
6 Dec - 7 Dec
Hyatt Regency Panama City
Front of property
Hotel San Felipe

Hotel San Felipe

4.0 star property
Casco Viejo
9.4 out of 10, Exceptional, (238)
"Really nice staff and property is in amazing location "
United States
Michael
The price is AED 386
AED 424 total
includes taxes & fees
16 Dec - 17 Dec
Hotel San Felipe
Daily full breakfast for a fee
Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo

4.5 star property
Casco Viejo
9.8 out of 10, Exceptional, (257)
"Many shops and restaurants nearby and the hotel is located in a beautiful area "
United States
Jerry
The price is AED 1,152
AED 1,267 total
includes taxes & fees
6 Dec - 7 Dec
Hotel La Compañía Casco Antiguo
2 outdoor pools, pool umbrellas, sun loungers
Radisson Hotel Panama Canal

Radisson Hotel Panama Canal

4.5 star property
Amador
8.4 out of 10, Very Good, (1012)
"Love the location and convenience "
United States
Patricia
The price is AED 256
AED 282 total
includes taxes & fees
23 Dec - 24 Dec
Radisson Hotel Panama Canal
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Panama City.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama
The price is AED 420 per night from Dec 8 to Dec 9
AED 420
AED 462 total
8 Dec - 9 Dec
includes taxes & fees
9/10 Wonderful! (4,609 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Panama City

The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch.

See all hotels in Panama City
Panoramic view at the Downtown of Panama City - Panama

Top Panama City Hotel Reviews

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

10/10 Excellent
"Buena estadia"
Rolando 2-night trip
Posted 3 days ago
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Frequently asked questions

What are the best 4-star hotels in Panama City?
Continental Hotel Panamá is a 4-star hotel in Panama City that ranks highly among Expedia travelers. A sauna and dining romance packages are just a couple of its amenities. Travelers also recommend Hotel El Panama by Faranda Grand, a member of Radisson Individuals. From premium bedding to Egyptian-cotton sheets, it offers conveniences that cater to every aspect of your relaxation and enjoyment.
How much does it cost to stay in a 4-star hotel in Panama City?
To lock in a 4-star hotel in Panama City that fits your budget, make use of Expedia's handy search filters. Take a look at the availability during your vacation dates and use our pricing filter to set your limit. You can also sort your results by the most affordable escape first.

  • Search for the lowest price from AED 462

What's the difference between 5-star and 4-star hotels in Panama City?
Offering a friendly traveler experience and upmarket décor, 4-star hotels are a fantastic option for your Panama City vacation. These types of accommodations generally feature loads of useful amenities that make it a breeze to unpack and unwind — think 24-hour room service, gyms and pools. Or enjoy even more lavishness at a 5-star hotel designed to indulge you in high-end perks and amenities. Concierge assistance, complimentary toiletries and fine dining are typically included at these swanky properties.

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